Female Infertility and Platelet-rich Plasma in Gynaecological Cases – IASRM Global
Female Infertility and Platelet-rich Plasma in Gynaecological Cases

Introduction – Platelet-rich plasma (PRP), a cutting-edge treatment, aims to encourage neovascularization, the production of healthy cells, and cellular regeneration.

An individual’s entire blood is used to create autologous PRP, which is subsequently centrifuged to eliminate red blood cells. In comparison to whole blood, the leftover plasma has a 5- to 10-fold higher oncentration of growth factors. Researchers from a variety of fields, including entistry, dermatology, urology, and gynaecology, have discovered that these growth factors support natural healing processes.

The theory guiding this therapeutic strategy was created from natural healing processes since the body initially responds to tissue injury by delivering platelets to the injured area. Platelets promote healing and draw stem cells to the location of the wound.

PRP in Aesthetic Gynaecology and Reproductive Medicine

In these two domains, platelet-rich plasma therapy is gradually beginning to take the place of antibiotics as the primary mode of treatment. This is due to the fact that PRP can also reverse the effects that an infection has had on a patient, whereas antibiotics can only inhibit infection triggers.

In order to cure persistent gynaecological and reproductive disorders, PRP can be used. Additionally, the therapy’s results show up sooner and last longer. The usage of platelets may be advantageous for patients with the following ailments:

  • Chronic Endometritis
  • Vaginal Dryness
  • Vulvodynia
  • Lichen Planus
  • Stress Urinary Incontinence
  • Vaginal Atrophy
  • Pre Mature Ovarian Failure
  • Vulvovaginal Rejuvenation
  • Early Menopause
  • Vaginismus,
  • And Cervical Leukoplakia
  • As an alternative method of treating persistent endometritis and endometriosis. Due to these illnesses’ capacity to trigger inflammatory processes, both naturally occurring pregnancies and in vitro fertilisation (IVF) cycles may suffer issues with embryo implantation.

    By improving progesterone receptor activation and lowering uterine inflammatory processes, the administration of PRP injections promotes healthy endometrial development and facilitates embryo implantation. It is feasible to continue IVF treatment after this therapy for improved outcomes.

  • In individuals with ovarian failure syndrome, PRP therapy encourages ovarian regeneration. PRP injections into the ovaries of menopausal and perimenopausal women might restart their menstrual periods. This allows the eggs that gave rise to the women’s ovaries to be received and later fertilised.
  • Role in infertility: PRP is used to help with and improve egg quantity and quality as well as to thicken the uterine lining and increase endometrial responsiveness during embryo transfer in a number of infertility therapies, including intrauterine injection and in vitro fertilisation (IVF). It is most typically used by patients who have a history of recurrent implantation failure (RIF), a condition in which multiple IVF transfers fail to result in pregnancy even though high-quality embryos were used each time. PRP is frequently tested before donor egg IVF, while it can also be used in conjunction with other treatments that focus on reproductive immunology and donor egg cycles.
  • Men who have been told they are infertile can now become parents thanks to cutting-edge PRP therapy for the testicles.


Many of the body’s processes depend on platelets, particularly those that affect the mucosa or skin. PRP, which is generated by the patient herself and is safer and more natural than goods with animal origins or that were donated by humans, is the pinnacle “body’s own” physiological product.

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